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Hepatorenal syndrome Pipeline Insight 2025

DelveInsight reports that the Hepatorenal Syndrome treatment pipeline includes over three key companies actively developing more than three therapeutic candidates for the condition.

Hepatorenal Syndrome Overview:

Hepatorenal syndrome (HRS) is a serious and life-threatening complication of liver cirrhosis, marked by a very poor prognosis. It is primarily characterized by intense narrowing of the kidney blood vessels (renal vasoconstriction), resulting from complex changes in both the systemic and splanchnic blood circulation, as well as disruptions in the balance between vasoconstrictive and vasodilatory factors. HRS generally arises in the setting of advanced circulatory dysfunction and is commonly linked with ascites and frequently accompanied by low sodium levels (hyponatremia).

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“Hepatorenal Syndrome Pipeline Insight 2025” report by DelveInsight provides a comprehensive analysis of the ongoing clinical development activities and growth prospects across the Hepatorenal Syndrome Therapeutics Market.

Key Takeaways from the Hepatorenal Syndrome Pipeline Report

• DelveInsight’s Hepatorenal Syndrome pipeline report depicts a robust space with 3+ active players working to develop 3+ pipeline therapies for Hepatorenal Syndrome treatment.

• In November 2025, Mallinckrodt presented data on TERLIVAZ® (terlipressin) injection for patients with Hepatorenal Syndrome (HRS) at the 2025 Annual Meeting of the American Association for the Study of Liver Diseases (AASLD).

• Key Hepatorenal Syndrome companies such as Noorik Biopharmaceuticals, Cumberland Pharmaceuticals, and others are evaluating new drugs for Hepatorenal Syndrome to improve the treatment landscape.

• Promising Hepatorenal Syndrome pipeline therapies in various stages of development include Ambrisentan, Ifetroban, and others.

Hepatorenal Syndrome Pipeline Analysis

The report provides insights into:

• The report provides detailed insights into the key companies that are developing therapies in the Hepatorenal Syndrome Market.

• The report also evaluates different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Hepatorenal Syndrome treatment.

• It analyzes the key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.

• It navigates the emerging drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.

• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Hepatorenal Syndrome market.

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Hepatorenal Syndrome Emerging Drugs

• Ambrisentan: Noorik Biopharmaceuticals

• Ifetroban: Cumberland Pharmaceuticals

Hepatorenal Syndrome Companies

Around three major companies are developing treatments for Hepatorenal Syndrome. Among them, Noorik Biopharmaceuticals and others have drug candidates currently in mid to late stages of development, specifically Phase II clinical trials.

DelveInsight’s report covers around 22+ products under different phases of clinical development like

• Late stage products (Phase III)

• Mid-stage products (Phase II)

• Early-stage product (Phase I) along with the details of

• Pre-clinical and Discovery stage candidates

• Discontinued & Inactive candidates

Hepatorenal Syndrome pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as

• Intravenous

• Subcutaneous

• Oral

• Intramuscular

Hepatorenal Syndrome Products have been categorized under various Molecule types such as

• Monoclonal antibody

• Small molecule

• Peptide

Download Sample Pages to Get an in-depth Assessment of the Emerging Hepatorenal Syndrome Therapies and Key Companies: Hepatorenal Syndrome Clinical Trials and advancements

Hepatorenal Syndrome Pipeline Therapeutic Assessment

• Hepatorenal Syndrome Assessment by Product Type

• Hepatorenal Syndrome By Stage

• Hepatorenal Syndrome Assessment by Route of Administration

• Hepatorenal Syndrome Assessment by Molecule Type

Download Hepatorenal Syndrome Sample report to know in detail about the Hepatorenal Syndrome treatment market @ Hepatorenal Syndrome Therapeutic Assessment

Table of Content

1. Report Introduction

2. Executive Summary

3. Hepatorenal Syndrome Current Treatment Patterns

4. Hepatorenal Syndrome – DelveInsight’s Analytical Perspective

5. Therapeutic Assessment

6. Hepatorenal Syndrome Late-Stage Products (Phase-III)

7. Hepatorenal Syndrome Mid-Stage Products (Phase-II)

8. Early Stage Products (Phase-I)

9. Pre-clinical Products and Discovery Stage Products

10. Inactive Products

11. Dormant Products

12. Hepatorenal Syndrome Discontinued Products

13. Hepatorenal Syndrome Product Profiles

14. Hepatorenal Syndrome Key Companies

15. Hepatorenal Syndrome Key Products

16. Dormant and Discontinued Products

17. Hepatorenal Syndrome Unmet Needs

18. Hepatorenal Syndrome Future Perspectives

19. Hepatorenal Syndrome Analyst Review

20. Appendix

21. Report Methodology

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Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Kritika Rehani
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Country: United States
Website: https://www.delveinsight.com/